Vectors for Mouse Cd74

Gene Information

  • Offical Gene Symbol Cd74
  • Species Mouse (Mus musculus)
  • Offical Full Name CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • Other Aliases CLIP; DHLAG; HLADG; Ia-GAMMA; Ii
  • Other Desigations H-2 class II histocompatibility antigen gamma chain; HLA-DR-GAMMA; Ia-associated invariant chain; MHC class II-associated invariant chain; class II-associated invariant chain peptide; dinucleotide microsatellite; histocompatibility: class II antigens, gamma chain of; ia antigen-associated invariant chain; ii chain; invariant polypeptide of major histocompatibility complex, class II antigen-associated
  • Gene Type protein-coding
  • 개요
    Enables MHC class II protein binding activity; cytokine receptor activity; and nitric-oxide synthase binding activity. Contributes to cytokine binding activity. Involved in several processes, including macrophage migration inhibitory factor signaling pathway; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; regulation of T cell differentiation; and thymic T cell selection. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and multivesicular body. Part of MHC class II protein complex; NOS2-CD74 complex; and macrophage migration inhibitory factor receptor complex. Is expressed in lower jaw; lower jaw incisor; lower jaw molar; and thymus primordium. Orthologous to human CD74 (CD74 molecule). [provided by Alliance of Genome Resources, Apr 2022]
  • NCBI Gene ID 16149
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | EnsemblUCSC Genome Browser View

Popular Vector Designs for Mouse Cd74(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Cd74 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Mouse Cd74 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Mouse Cd74 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Mouse Cd74 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Mouse Cd74 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Cd74 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Mouse Cd74 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Mouse Cd74 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Mouse Cd74 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Mouse Cd74 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Mouse Cd74 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Mouse Cd74 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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